Dr. rer. nat. Heike Helmholz
Scientist
Marine Bioanalytical Chemistry (KBA)
Phone: +49 (0)4152 87-1844
Fax: +49 (0)4152 87-1875
Deputy Head of the Department
Research field
- Effect-based characterization of potential hazardous compounds (Toxicology)
- Bio-specific, molecular Interaction Analysis (BIA)
- Isolation and structure characterization of proteins (Proteinbiochemistry)
- Cultivation of mammalian and fish cells as targets (Bio-assays)
Scientific Career
1990 Abitur (high school graduation)
1990 - 1995 Undergraduate study in Biopharmacology at the Ernst-Moritz-Arndt University of Greifswald
1995 Diploma: Institute for Pharmacology and Toxicology University Greifswald
Thesis: Influences of Histamin, H2-Receptor- and H+/K+ ATPase antagonists on the oxydative and konjugative drug metabolism Degree in Biopharmacology
1995-1998 Scientific Assistent Institute for Pharmacy/Pharmaceutical Biology University Greifswald
Dissertation Thesis: Investigation of immunmodulatoric active compounds of marine fungi with special focus on the marine basidiomycete Nia vibrissa (Moore & Meyers)
1998-present Scientific Assistent Helmholtz-Zentrum Geesthacht Research Centre, Geesthacht
Selected Publications
Helmholz H (2010): Selective toxin-lipid membrane interactions of natural, haemolytic Scyphozoan toxin analyzed by Surface Plasmon Resonance. Biochimica et Biophysica Acta - Biomembranes 1798, 1944-1952
Helmholz H, Naatz S, Lassen S, Prange A (2008): Isolation of a cytotoxic glycoprotein from the Scyphozoa Cyanea lamarckii by lectin affinity chromatography and characterization of molecule interactions by surface plasmon resonsnace. Journal of Chromatography B 871, 60-66
Helmholz H, Ruhnau C, Schütt C, Prange A (2007): Comparative study on the cell toxicity and enzymatic activity of two northern scyphozoan species Cyanea capillata (L.) and Cyanea lamarckii (Peron & Leslueur). Toxicon 50, 53-64
